H. Pylori Testing

This test is used to aid in the diagnosis of H. pylori (Helicobacter pylori) bacteria infections, and/or to determine the cause of chronic type B gastritis or ulcers of the stomach or duodenum.

This test looks for antigens that develop as a result of H. Pylori presence, indicating there is currently an H. Pylori infection or that there was an H. Pylori infection in the past 12-18 months.

About Helicobacter Pylori

Helicobacter pylori is a spiral-shaped gram-negative bacillus, for which the natural reservoir is the gastrointestinal tract of humans. The organism is unique in its ability to survive the acidic pH of gastric fluids. Although most infected individuals will not develop clinically significant complications, infection with this organism has been associated with increased risk of developing duodenal and gastric ulcers, non-ulcer dyspepsia, gastric carcinoma, and mucosa-associated lymphoid tissue lymphoma. To detect infection, either an invasive (requiring endoscopy) or noninvasive testing algorithm is recommended based on patient demographics and symptoms.

H. Pylori bacteria can hide in the protective mucosal lining of the stomach, out of reach from immune cells. This lining protects the stomach from the gastric acids it creates to digest food. H. Pylori can change the stomach’s acidity to help ensure the bacteria’s own survival. H. Pylori can cause ulcers in the stomach or small intestine, as well as a condition called gastritis in which the inside of the stomach becomes inflamed.